Identification | Back Directory | [Name]
AL-9
(HCV inhibitor AL-9) | [CAS]
869218-90-6 | [Synonyms]
AL-9 AL-9
(HCV inhibitor AL-9) | [Molecular Formula]
C23H22N4O3 | [MDL Number]
MFCD32184112 | [MOL File]
869218-90-6.mol | [Molecular Weight]
402.45 |
Chemical Properties | Back Directory | [Boiling point ]
631.3±55.0 °C(Predicted) | [density ]
1.335±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
13.84±0.10(Predicted) | [color ]
Light yellow to yellow |
Hazard Information | Back Directory | [Description]
AL-9 is a replication inhibitor of GT-1b and GT-2a. | [Uses]
AL-9 is a inhibitor of PI4KIIIα, with the IC50 of 0.57 μM, that can inhibit HCV replication[1]. | [References]
[1] Annalisa Bianco, et al. Metabolism of phosphatidylinositol 4-kinase IIIα-dependent PI4P Is subverted by HCV and is targeted by a 4-anilino quinazoline with antiviral activity. PLoS Pathog. 2012;8(3):e1002576. DOI:10.1371/journal.ppat.1002576 |
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