ChemicalBook--->CAS DataBase List--->86933-74-6

86933-74-6

86933-74-6 Structure

86933-74-6 Structure
IdentificationBack Directory
[Name]

NEUROKININ A
[CAS]

86933-74-6
[Synonyms]

NKA
SUBSTANCE K
NEUROMEDIN L
NEUROKININ A
A-neurokinin
α-neurokinin
HKTDSFVGLM-NH2
ALPHA-NEUROKININ
NEUROKININ ALPHA
Neurokinin A [NKA]
NEUROKININ A (PORCINE)
NEUROKININ A USP/EP/BP
SUBSTANCE K (HUMAN, PORCINE, RAT, MOUSE)
NEUROKININ A (HUMAN, PORCINE, RAT, MOUSE)
NEUROMEDIN L (HUMAN, PORCINE, RAT, MOUSE)
α-Neurokinin, Neuromedin L, Substance K
HIS-LYS-THR-ASP-SER-PHE-VAL-GLY-LEU-MET-NH2
NKA, Substance K, Neurokinin a, NeuroMedin L
Neurokinin A: Substance K: Neuromedin L: NKA
H-HIS-LYS-THR-ASP-SER-PHE-VAL-GLY-LEU-MET-NH2
Neurokinin A,α-Neurokinin,Neuromedin L,Substance K, >98%
Neurokinin A NKA, Substance K, Neurokinin α, NeuroMedin L
Neurokinin A NKA, Substance K, Neurokinin α, NeuroMedin L
L-His-L-Lys-L-Thr-L-Asp-L-Ser-L-Phe-L-Val-Gly-L-Leu-L-Met-NH2
L-Methioninamide, L-histidyl-L-lysyl-L-threonyl-L-α-aspartyl-L-seryl-L-phenylalanyl-L-valylglycyl-L-leucyl-
[Molecular Formula]

C50H80N14O14S
[MDL Number]

MFCD00167560
[MOL File]

86933-74-6.mol
[Molecular Weight]

1133.33
Chemical PropertiesBack Directory
[Boiling point ]

1610.7±65.0 °C(Predicted)
[density ]

1.305±0.06 g/cm3(Predicted)
[RTECS ]

PC4360090
[storage temp. ]

-20°C
[form ]

White to off-white powder.
[pka]

4.17±0.10(Predicted)
[color ]

White to off-white
[Water Solubility ]

Soluble in water at 1mg/ml
[Sequence]

H-His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met-NH2
[InChIKey]

HEAUFJZALFKPBA-UHFFFAOYSA-N
[SMILES]

CSCCC(NC(=O)C(CC(C)C)NC(=O)CNC(=O)C(NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)C(CC(O)=O)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(N)Cc2cnc[nH]2)C(C)O)C(C)C)C(N)=O
Safety DataBack Directory
[WGK Germany ]

3
[F ]

10-21
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

Neurokinin A is an endogenous tachykinin agonist with preference for the NK-2R.
[General Description]

Neurokinin A is an 11 amino acid peptide. It is a member of tachykinin family, which includes neurokinin A, neurokinin B, neuropeptide K, neuropeptide Y and hemokinin-1. The gene encoding neurokinin A is localized on human chromosome 7q21.3.
[Biochem/physiol Actions]

Neurokinin A improves the multiplication and paracrine ability of stem cells acquired from adipose in vitro. It participates in the movement of several organ tracts, triggers glandular secretion and controls autonomic reflexes. Neurokinin A plays an important role in neuroimmune and systemic autoimmune/inflammatory conditions like multiple sclerosis (MS), rheumatoid arthritis, inflammatory bowel disease and also in infections and cancer.
[storage]

Desiccate at -20°C
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