| Identification | Back Directory | [Name]
(1R,3S)-REL-3-(3,4-DICHLOROPHENYL)-2,3-DIHYDRO-N-METHYL-1H-INDEN-1-AMINE HYDROCHLORIDE | [CAS]
86939-10-8 | [Synonyms]
Indatraline
Indatralinum
IndatralineHCl
( -)-trans-3-(3,4-Dichlorophenyl)-N-methyl-1-indanamine
(1R)-1α-Methylamino-2,3-dihydro-3β-(3,4-dichlorophenyl)-1H-indene
1H-Inden-1-amine, 3-(3,4-dichlorophenyl)-2,3-dihydro-N-methyl-, (1R,3S)-rel- | [Molecular Formula]
C16H15Cl2N | [MDL Number]
MFCD06804607 | [MOL File]
86939-10-8.mol | [Molecular Weight]
292.2 |
| Hazard Information | Back Directory | [Uses]
Indatraline (Lu 19005 free base) is a long-acting monoamine reuptake inhibitor that can be used in the research of neurological diseases[1]. | [Definition]
ChEBI: (1R,3S)-3-(3,4-dichlorophenyl)-N-methyl-2,3-dihydro-1H-inden-1-amine is a member of indanes. | [Biological Activity]
Potent monoamine uptake inhibitor. Inhibits transporters for 5-HT (SERT), dopamine (DAT) and noradrenalin (NET) (K i values are 0.42, 1.7 and 5.8 nM respectively). Centrally active following systemic administration in vivo . | [References]
[1] Negus S S, et al. Effects of the long-acting monoamine reuptake inhibitor indatraline on cocaine self-administration in rhesus monkeys[J]. Journal of Pharmacology and Experimental Therapeutics, 1999, 291(1): 60-69. PMID:10490887 |
|
| Company Name: |
|
| Tel: |
821-50328103-801 18930552037 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList13285/0.htm |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
guoyungurui
|
| Tel: |
18162595016; 18162595016 |
| Website: |
https://www.chemicalbook.com/supplier/25521782/ |
|