| Identification | Back Directory | [Name]
OBESTATIN (RAT) | [CAS]
869705-22-6 | [Synonyms]
OBESTATIN (RAT)
Obestatin (mouse)
Obestatin (mouse, rat)
Obestatin, rat, mouse, gerbil
Obestatin mouse, rat synthetic
H-PHE-ASN-ALA-PRO-PHE-ASP-VAL-GLY-ILE-LYS-LEU-SER-GLY-ALA-GLN-TYR-GLN-GLN-HIS-GLY-ARG-ALA-LEU-NH2
L-Leucinamide, L-phenylalanyl-L-asparaginyl-L-alanyl-L-prolyl-L-phenylalanyl-L-α-aspartyl-L-valylglycyl-L-isoleucyl-L-lysyl-L-leucyl-L-serylglycyl-L-alanyl-L-glutaminyl-L-tyrosyl-L-glutaminyl-L-glutaminyl-L-histidylglycyl-L-arginyl-L-alanyl- | [Molecular Formula]
C114H174N34O31 | [MDL Number]
MFCD08458632 | [MOL File]
869705-22-6.mol | [Molecular Weight]
2516.81 |
| Chemical Properties | Back Directory | [storage temp. ]
Desiccate at -20°C | [solubility ]
deionized water: soluble0.5-1mg/mL | [form ]
lyophilized powder | [color ]
white | [Sequence]
Phe-Asn-Ala-Pro-Phe-Asp-Val-Gly-Ile-Lys-Leu-Ser-Gly-Ala-Gln-Tyr-Gln-Gln-His-Gly-Arg-Ala-Leu-NH2 |
| Hazard Information | Back Directory | [Uses]
Obestatin(rat), encoded by the Ghrelin gene, is a cpeptide, comprised of 23 amino acids. Obestatin(rat) suppresses food intake, inhibits jejunal contraction, and decreases body-weight gain. Obestatin is an endogenous ligand of G-protein coupled receptor 39 (GPR39). Obestatin(rat) has anti-inflammatory, anti-myocardial infarction and antioxidant activities[1][2]. | [References]
[1] Azadeh Toosi, et al. Obestatin Improve Spatial Memory Impairment in a Rat Model of Fetal Alcohol Spectrum Disorders via Inhibiting Apoptosis and Neuroinflammation. Neuropeptides. 2019 Apr;74:88-94. DOI:10.1016/j.npep.2019.01.001
[2] Science. 2005 Nov 11;310(5750):996-9. doi: 10.1126/science.1117255. DOI:10.1126/science.1117255 |
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