| Identification | Back Directory | [Name]
4-[3-(2,4-Dimethoxy-3-methylphenyl)propyl]-1,3-benzenediol | [CAS]
869743-37-3 | [Synonyms]
UP302
Nivitol
4-[3-(2,4-Dimethoxy-3-methylphenyl)propyl]-1,3-benzenediol
1,3-Benzenediol, 4-[3-(2,4-dimethoxy-3-methylphenyl)propyl]-
1-(2,4-dihydroxyphenyl)-3-(2,4-dimethoxy-3-methylphenyl)propane | [Molecular Formula]
C18H22O4 | [MDL Number]
MFCD24039003 | [MOL File]
869743-37-3.mol | [Molecular Weight]
302.36 |
| Chemical Properties | Back Directory | [Boiling point ]
460.166±40.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.160±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
9.939±0.20(predicted) | [Cosmetics Ingredients Functions]
ANTIOXIDANT
SKIN CONDITIONING | [InChI]
InChI=1S/C18H22O4/c1-12-17(21-2)10-8-14(18(12)22-3)6-4-5-13-7-9-15(19)11-16(13)20/h7-11,19-20H,4-6H2,1-3H3 | [InChIKey]
HOCCFHXBGWEJEQ-UHFFFAOYSA-N | [SMILES]
C1(O)=CC=C(CCCC2=CC=C(OC)C(C)=C2OC)C(O)=C1 |
| Hazard Information | Back Directory | [Uses]
Nivitol is a miscellaneous reagent used in synthesis of a novel tyrosinase inhibitor which acts as a melanin inhibitor. | [Anticancer Research]
Researchers assessed the in vitro antitumor activity of UP302 in different tumor cells. It inhibited the growth of certain cancer cell lines and especially in leukemia cells[1]. | [Source]
4-[3-(2,4-Dimethoxy-3-methylphenyl)propyl]-1,3-benzenediol (UP302) can be found in the medicinal plant Dianella ensifolia. | [References]
[1] Wei, J., Zhong, X., Peng, H., Cui, B., Yue, X., Sun, Z., & Shi, J. (2024). Dimethoxytolyl propylresorcinol induces apoptosis and mitophagy in human leukemia cells through the PI3K/AKT pathway. Journal of Cancer, 15 1, 103–112. https://doi.org/10.7150/jca.89243
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