| Identification | Back Directory | [Name]
7-Oxabicyclo[2.2.1]hept-5-ene-2-sulfonic acid, 5,6-bis(4-hydroxyphenyl)-, phenyl ester, (1R,2S,4R)-rel- | [CAS]
870614-18-9 | [Synonyms]
OBHS
7-Oxabicyclo[2.2.1]hept-5-ene-2-sulfonic acid, 5,6-bis(4-hydroxyphenyl)-, phenyl ester, (1R,2S,4R)-rel- | [Molecular Formula]
C24H20O6S | [MOL File]
870614-18-9.mol | [Molecular Weight]
436.48 |
| Chemical Properties | Back Directory | [Melting point ]
142-143 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3)) | [Boiling point ]
679.4±55.0 °C(Predicted) | [density ]
1.50±0.1 g/cm3(Predicted) | [pka]
10.13±0.30(Predicted) |
| Hazard Information | Back Directory | [Uses]
OBHS is an estrogen receptor α (ERα) inhibitor. OBHS can also be used as a blowing agent[1][2]. | [References]
[1] He M, et al. Design, synthesis and biological evaluation of novel dual-acting modulators targeting both estrogen receptor α (ERα) and lysine-specific demethylase 1 (LSD1) for treatment of breast cancer. Eur J Med Chem. 2020 Jun 1;195:112281. DOI:10.1016/j.ejmech.2020.112281
[2] Srikham J, et al. Foamability of Natural rubber (NR)/Poly (butylenes adipate-co-terephthalate)(PBAT) Thermoplastic Vulcanizate with OBSH as a blowing agent. 2020 IOP Conf. Ser.: Mater. Sci. Eng. 965 012018. |
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