ChemicalBook--->CAS DataBase List--->870710-02-4

870710-02-4

870710-02-4 Structure

870710-02-4 Structure
IdentificationBack Directory
[Name]

4(5H)-Thiazolone, 2-[[(1S)-1-(2-fluorophenyl)ethyl]amino]-5-methyl-5-(trifluoromethyl)-, (5S)-
[CAS]

870710-02-4
[Synonyms]

BVT116429
BVT-116429
BVT 116429
4(5H)-Thiazolone, 2-[[(1S)-1-(2-fluorophenyl)ethyl]amino]-5-methyl-5-(trifluoromethyl)-, (5S)-
[Molecular Formula]

C13H12F4N2OS
[MDL Number]

MFCD09970887
[MOL File]

870710-02-4.mol
[Molecular Weight]

320.31
Chemical PropertiesBack Directory
[Boiling point ]

346.1±52.0 °C(Predicted)
[density ]

1.41±0.1 g/cm3(Predicted)
[pka]

-0.21±0.40(Predicted)
Hazard InformationBack Directory
[Description]

BVT-116429 is a 11β-HSD1 inhibitor.
[Uses]

BVT-116429 is an 11βHSD1 inhibitor with the activity of increasing adiponectin concentration and improving glucose homeostasis in diabetic mice. BVT-116429 can increase plasma adiponectin levels in diabetic KKAy mice, reduce basal insulin levels, and reduce fasting blood glucose levels after 10 days of inhibition, similar to the effect of rosiglitazone.
[References]

[1] Inhibition of 11betaHSD1 with the S-phenylethylaminothiazolone BVT116429 increases adiponectin concentrations and improves glucose homeostasis in diabetic KKAy mice DOI:10.1186/1471-2210-8-3
870710-02-4 suppliers list
Company Name: TargetMol Chemicals Inc.
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Website: https://www.targetmol.com/
Company Name: TargetMol Chemicals Inc.
Tel: +8613564774135 , +8613564774135
Website:
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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