| Identification | Back Directory | [Name]
3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trione | [CAS]
871700-24-2 | [Synonyms]
CB42623933
Trametinib INT
cyclopropylthiadiazolamine
3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H
3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H
3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethyl-1H,8H-pyrido[2,3-d]pyrimidine-2,4,7-trione
3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-diMethylpyrido[2,3-d]pyriMidine-2,4,7(1H,3H,8H)-trione
Pyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione, 3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethyl- | [Molecular Formula]
C18H15FIN3O4 | [MDL Number]
MFCD18207185 | [MOL File]
871700-24-2.mol | [Molecular Weight]
483.23 |
| Chemical Properties | Back Directory | [Boiling point ]
518.2±60.0 °C(Predicted) | [density ]
1.94±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C(protect from light) | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
4.50±1.00(Predicted) | [color ]
White to Off-White | [InChI]
InChI=1S/C18H15FIN3O4/c1-8-14(24)13-15(21(2)16(8)25)23(12-6-3-9(20)7-11(12)19)18(27)22(17(13)26)10-4-5-10/h3,6-7,10,24H,4-5H2,1-2H3 | [InChIKey]
MHHFXMZMCYWCJQ-UHFFFAOYSA-N | [SMILES]
C1(=O)N(C2CC2)C(=O)C2C(O)=C(C)C(=O)N(C)C=2N1C1=CC=C(I)C=C1F |
| Hazard Information | Back Directory | [Uses]
3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7-trione is used for treatment of cancer and rheumatic diseases |
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| Company Name: |
SPIRO PHARMA
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| Telephone: |
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| Website: |
www.spiropharma.com.cn |
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