| Identification | Back Directory | [Name]
PAM3-CYS-SER-SER-ASN-ALA-OH | [CAS]
87173-03-3 | [Synonyms]
anine
MITOGENIC PENTAPEPTIDE
Tripalmitoyl pentapeptide
PAM3-CYS-SER-SER-ASN-ALA-OH
PaM3Cys-Ser-Ser-Asn-Ala-OH, PaM3CSSNA
PALMITOYL-CYS ((RS)-2,3-DI(PALMITOYLOXY)-PROPYL)-SER-SER-ASN-ALA-OH
S-[2,3-BIS(PALMITOYLOXY)-(2RS)-PROPYL]-N-PALMITOYL-(R)-CYS-SER-SER-ASN-ALA-OH
2,3-bis(palmitoyloxy)-2-propyl-n-palmitoyl-cysteinyl-seryl-seryl-asparaginyl-al
2,3-bis(palmitoyloxy)-2-propyl-N-palmitoyl-cysteinyl-seryl-seryl-asparaginyl-alanine | [Molecular Formula]
C67H124N6O14S | [MDL Number]
MFCD00237176 | [MOL File]
87173-03-3.mol | [Molecular Weight]
1269.8 |
| Chemical Properties | Back Directory | [Boiling point ]
1304.2±65.0 °C(Predicted) | [density ]
1.078±0.06 g/cm3(Predicted) | [storage temp. ]
-15°C
| [pka]
3.36±0.10(Predicted) | [Sequence]
{Palmitoyl}-{Cys((RS)-2,3-di(palmitoyloxy)-propyl)}-Ser-Ser-Asn-Ala |
| Hazard Information | Back Directory | [Uses]
Mitogenic Pentapeptide (Tripalmitoyl pentapeptide) is an effective activator of B lymphocyte mitogen and polyclonal. Mitogen Pentapeptide is a synthetic N-terminal analog of E. coli outer membrane lipoproteins (cysteinyl-seryl-seryl-asparaginyl-alanine). Mitogenic Pentapeptide can be used for the study of immune adjuvants[1][2]. | [References]
[1] Bessler WG, et al. Synthetic lipopeptide analogs of bacterial lipoprotein are potent polyclonal activators for murine B lymphocytes. J Immunol. 1985 Sep;135(3):1900-5. PMID:3874908
[2] Lex A, et al. A synthetic analogue of Escherichia coli lipoprotein, tripalmitoyl pentapeptide, constitutes a potent immune adjuvant. J Immunol. 1986 Oct 15;137(8):2676-81. PMID:3531339 |
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