| Identification | Back Directory | [Name]
(4Z,7S,9E,11E,13Z,15E,17S,19Z)-7,8,17-trihydroxydocosa-4,9,11,13,15,19-hexaenoic acid | [CAS]
872993-05-0 | [Synonyms]
RVD1
Resolvin D1
resolvin D1, CID73755062
Resolvin D1 Exclusive
OIWTWACQMDFHJG-CCFUIAGSSA-N
Resolvin D1 MaxSpec? Standard
(4Z,7S,9E,11E,13Z,15E,17S,19Z)-7,8,17-trihydroxydocosa-4,9,11,13,15,19-hexaenoic acid
(4Z,7S,8S,9E,11E,13Z,15E,17S,19Z)-7,8,17-TRIHYDROXYDOCOSA-4,9,11,13,15,19-HEXAENOIC ACID
4,9,11,13,15,19-Docosahexaenoic acid, 7,8,17-trihydroxy-, (4Z,7S,8R,9E,11E,13Z,15E,17S,19Z)- | [Molecular Formula]
C22H32O5 | [MDL Number]
MFCD11045851 | [MOL File]
872993-05-0.mol | [Molecular Weight]
376.49 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -80°C,protect from light | [solubility ]
DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.05 mg/ml | [form ]
Liquid | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Uses]
Resolvin D1 is used to protect against hepatic injury and heart failure, specifically in rats. Also used as a means to attenuate the inflammatory reaction. | [in vivo]
Resolvin D1 (RvD1) (100-1000 ng; i.p.; daily on days 10) improves RA (rheumatoid arthritis) clinical endpoints in arthritic mice[3]. | Animal Model: | 18-20?g thirty 8-week-old female DBA/1J mice (collagen antibody-induced arthritis (CAIA))[3] | | Dosage: | 100, 500, and 1000?ng (or 1000 ng, daily on days 4-10) | | Administration: | i.p. injection; daily on days 10 | | Result: | Exhibit a reduced arthritic score. |
| [IC 50]
Human Endogenous Metabolite |
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