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873582-78-6

873582-78-6 Structure

873582-78-6 Structure
IdentificationBack Directory
[Name]

Glycine, L-seryl-L-isoleucyl-L-arginyl-L-α-glutamyl-L-leucyl-L-α-glutamyl-L-alanyl-L-arginyl-L-isoleucyl-L-arginyl-L-α-glutamyl-L-leucyl-L-α-glutamyl-L-leucyl-L-arginyl-L-isoleucyl-
[CAS]

873582-78-6
[Synonyms]

Glycine, L-seryl-L-isoleucyl-L-arginyl-L-α-glutamyl-L-leucyl-L-α-glutamyl-L-alanyl-L-arginyl-L-isoleucyl-L-arginyl-L-α-glutamyl-L-leucyl-L-α-glutamyl-L-leucyl-L-arginyl-L-isoleucyl-
[Molecular Formula]

C88H157N29O27
[MOL File]

873582-78-6.mol
[Molecular Weight]

2053.37
Chemical PropertiesBack Directory
[density ]

1.44±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[Sequence]

Ser-Ile-Arg-Glu-Leu-Glu-Ala-Arg-Ile-Arg-Glu-Leu-Glu-Leu-Arg-Ile-Gly
Hazard InformationBack Directory
[Uses]

CCβ is a simple 17-amino acid peptide designed in research. CCβ is able to mimic the conformational transition of proteins from α-helix to β-sheet, which is a key step in the aggregation of proteins associated with many diseases, such as Alzheimer's disease and prion disease. CCβ can be used to study diseases related to protein aggregation[1].
[References]

[1] Ding F, et al. Direct observation of protein folding, aggregation, and a prion-like conformational conversion[J]. Journal of Biological Chemistry, 2005, 280(48): 40235-40240. DOI:10.1074/jbc.M506372200
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