| Identification | Back Directory | [Name]
MPEG4-NHS | [CAS]
874208-94-3 | [Synonyms]
MPEG4-NHS
mPEG4-SPA
m-PEG5-NHS ester
mPEG4-CH2CH2COONHS Ester
4,7,10,13,16-Pentaoxaheptadecanoic acid, 2,5-dioxo-1-pyrrolidinyl ester
3-(2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-propionicacid2.5-dioxo-pyrrolidin-1-ylester | [Molecular Formula]
C16H27NO9 | [MDL Number]
MFCD20227375 | [MOL File]
874208-94-3.mol | [Molecular Weight]
377.39 |
| Chemical Properties | Back Directory | [Boiling point ]
467.9±55.0 °C(Predicted) | [density ]
1.22±0.1 g/cm3(Predicted) | [solubility ]
Soluble in DMSO, DCM, DMF | [form ]
Liquid | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Description]
m-PEG5-NHS ester is a PEG linker containing an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer increases solubility in aqueous media. | [Uses]
m-PEG5-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. | [References]
[1] Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67. DOI:10.3762/bjoc.11.74 |
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