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874459-98-0

874459-98-0 Structure

874459-98-0 Structure
IdentificationBack Directory
[Name]

3-(2-PyridylcarbaMoyl)benzeneboronic acid
[CAS]

874459-98-0
[Synonyms]

(3-(Pyridin-2-ylcarbamoyl)phenyl)boronic acid
3-(2-PyridylcarbaMoyl)benzeneboronic acid, 97%
Boronic acid, B-[3-[(2-pyridinylamino)carbonyl]phenyl]-
(3-(pyridin-2-ylcarbamoyl) phenyl)boronic acidQ: What is (3-(pyridin-2-ylcarbamoyl) phenyl)boronic acid Q: What is the CAS Number of (3-(pyridin-2-ylcarbamoyl) phenyl)boronic acid
[Molecular Formula]

C12H11BN2O3
[MDL Number]

MFCD28167454
[MOL File]

874459-98-0.mol
[Molecular Weight]

242.04
Chemical PropertiesBack Directory
[density ]

1.33±0.1 g/cm3(Predicted)
[pka]

7.87±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

[3-[(2-pyridinylamino)carbonyl]phenyl]boronic Acid is an impurity of Acalabrutinib (A115605), is an experimental anti-cancer drug and a selective Bruton''s tyrosine kinase (BTK) inhibitor. This kinase transmits signals from B-cell Receptor (BCR), and thus any genetic BTK mutation causes B-Cell immunodeficiency. Therefore, BTK inhibitors targeting B-cell signaling has shown great promise for the treatment of chronic lymphocytic leukemia (CLL).
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