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87462-66-6

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87462-66-6 Structure

87462-66-6 Structure
IdentificationBack Directory
[Name]

7-Iodo-1-heptyne
[CAS]

87462-66-6
[Synonyms]

7-Iodo-1-heptyne
7-Iodohept-1-yne
1-Heptyne, 7-iodo-
[Molecular Formula]

C7H11I
[MDL Number]

MFCD30475372
[MOL File]

87462-66-6.mol
[Molecular Weight]

222.07
Chemical PropertiesBack Directory
[Boiling point ]

197.8±23.0 °C(Predicted)
[density ]

1.514±0.06 g/cm3(Predicted)
Hazard InformationBack Directory
[Uses]

7-Iodohept-1-yne is a PROTAC Linker that can be used to synthesize PROTAC QZ2135 (HY-170852)[1].
[References]

[1] Zhang Q, et al. Discovery of an Efficacious RET PROTAC Degrader with Enhanced Antiproliferative Activity against Resistant Cancer Cells Harboring RET Solvent-Front Mutations. J Med Chem. 2025 Jan 9;68(1):753-775. DOI:10.1021/acs.jmedchem.4c02692
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