ChemicalBook--->CAS DataBase List--->874638-94-5

874638-94-5

874638-94-5 Structure

874638-94-5 Structure
IdentificationBack Directory
[Name]

(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate
[CAS]

874638-94-5
[Synonyms]

Sofosbuvir imp-6
Sofosbuvir Impurity X
2'-epi-Sofosbuvir Desphosphate
Sofosbuvir Dibenzoyl Amino Impurity
(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate
Benzamide, N-[1-[(2R)-3,5-di-O-benzoyl-2-deoxy-2-fluoro-2-methyl-α-D-erythro-pentofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-
N-[1-[(2R)-3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2-methyl-alpha-D-erythro-pentofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]benzamide
Sofosbuvir impurity 21/(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate
[Molecular Formula]

C31H26FN3O7
[MDL Number]

MFCD27918668
[MOL File]

874638-94-5.mol
[Molecular Weight]

571.56
Chemical PropertiesBack Directory
[Melting point ]

174-175 °C(Solv: dichloromethane (75-09-2); hexane (110-54-3))
[density ]

1.34±0.1 g/cm3(Predicted)
[pka]

8.51±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

2’-epi-Sofosbuvir Desphosphate is possible metabolite of Sofosbuvir (P839640) which is a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C.
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