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874967-67-6

874967-67-6 Structure

874967-67-6 Structure
IdentificationBack Directory
[Name]

Mixture of 2′-[(1RS,2RS)-1,1′-Bicycloprop-2-yl]-3-(difluoromethyl)-1-methylpyrazole-4-carboxanilide and 2′-[(1RS,2SR)-1,1′-bicycloprop-2-yl]-3-(difluoromethyl)-1-methylpyrazole-4-carboxanilide
[CAS]

874967-67-6
[Synonyms]

Sedaxane
Sedaxane Solution
Sedaxane, mixture of isomers
Sedaxane@100 μg/mL in Methanol
Sedaxane Solution in Methanol, 100μg/mL
1H-Pyrazole-4-carboxamide, N-(2-[1,1'-bicyclopropyl]-2-ylphenyl)-3-(difluoromethyl)-1-methyl-
Mixture of 2′-[(1RS,2RS)-1,1′-Bicycloprop-2-yl]-3-(difluoromethyl)-1-methylpyrazole-4-carboxanilide and 2′-[(1RS,2SR)-1,1′-bicycloprop-2-yl]-3-(difluoromethyl)-1-methylpyrazole-4-carboxanilide
[Molecular Formula]

C18H19F2N3O
[MDL Number]

MFCD22373629
[MOL File]

874967-67-6.mol
[Molecular Weight]

331.36
Chemical PropertiesBack Directory
[Boiling point ]

397.8±42.0 °C(Predicted)
[density ]

1.43±0.1 g/cm3(Predicted)
[solubility ]

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Sonicated)
[pka]

12.23±0.70(Predicted)
[Henry's Law Constant]

2.5×105 mol/(m3Pa) at 25℃, Maniere et al. (2011)
[EPA Substance Registry System]

1H-Pyrazole-4-carboxamide, N-(2-[1,1'-bicyclopropyl]-2-ylphenyl)-3-(difluoromethyl)-1-methyl- (874967-67-6)
Safety DataBack Directory
[Symbol(GHS) ]

Environment (GHS09)
GHS09
[Signal word ]

Warning
[Hazard statements ]

H410
[Precautionary statements ]

P273-P501
[Hazard Codes ]

N
[Risk Statements ]

50/53
[Safety Statements ]

60-61
[RIDADR ]

UN 3077 9 / PGIII
Hazard InformationBack Directory
[Uses]

Sedaxane is a broad-spectrum seed treatment fungicide used for control of seed- and soil-borne diseases in a broad range of crops. It inhibits fungal respiration by binding to the succinate dehydrogenase complex in the fungal mitochondrium.
[Definition]

ChEBI: N-{2-[1,1'-bi(cyclopropyl)-2-yl]phenyl}-3-(difluoromethyl)-1-methyl-1pyrazole-4-carboxamide is an aromatic amide obtained by formal condensation of the carboxy group of 3-(difluoromethyl)-1-methylpyrazole-4-carboxylic acid with the amino group of 2-[1,1'-bi(cyclopropyl)-2-yl]aniline. It is an aromatic amide, an organofluorine compound, a member of pyrazoles, a ring assembly and a member of cyclopropanes.
[Production Methods]

Sedaxane is commercially produced via a process that involves constructing a difluoromethyl-substituted pyrazole ring and coupling it with a bicyclopropyl-aryl amide moiety. This multi-step process requires precise control of stereochemistry and fluorination to ensure biological activity and environmental stability.
[Mechanism of action]

Broad-spectrum, Succinate dehydrogenase inhibitor
[Pesticide Type]

Fungicide
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