| Identification | Back Directory | [Name]
N-{4-[(2-chloro-6-fluorobenzyl)oxy]-3-methoxybenzyl}-2-(morpholin-4-yl)ethanamine | [CAS]
875005-43-9 | [Synonyms]
GLP-1R modulator C16
N-{4-[(2-chloro-6-fluorobenzyl)oxy]-3-methoxybenzyl}-2-(morpholin-4-yl)ethanamine
4-Morpholineethanamine, N-[[4-[(2-chloro-6-fluorophenyl)methoxy]-3-methoxyphenyl]methyl]- | [Molecular Formula]
C21H26ClFN2O3 | [MOL File]
875005-43-9.mol | [Molecular Weight]
408.89 |
| Chemical Properties | Back Directory | [Boiling point ]
516.8±45.0 °C(Predicted) | [density ]
1.213±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
8.80±0.19(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
GLP-1R modulator C16 is an allosteric modulator enhancing GLP-1 binding to GLP-1R via a transmembrane site (EC50 8.43 ± 3.82 μM). | [References]
[1] Wang J, et al. Allosteric Modulators Enhancing GLP-1 Binding to GLP-1R via a Transmembrane Site. ACS Chem Biol. 2021 Nov 19;16(11):2444-2452. DOI:10.1021/acschembio.1c00552 |
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