| Identification | Back Directory | [Name]
SPIPERONE N-METHYL- HCL | [CAS]
87539-19-3 | [Synonyms]
3-N-methylspiperone
SPIPERONE N-METHYL- HCL
SPIPERONE, N-METHYL HYDROCHLORIDE DOPAMI NERGIC D2 ANTAG | [Molecular Formula]
C24H28FN3O2 | [MDL Number]
MFCD00083200 | [MOL File]
87539-19-3.mol | [Molecular Weight]
409.5 |
| Chemical Properties | Back Directory | [Boiling point ]
608.0±55.0 °C(Predicted) | [density ]
1.25±0.1 g/cm3(Predicted) | [solubility ]
0.1 M HCl: soluble | [form ]
solid | [pka]
9.03±0.20(Predicted) | [color ]
light yellow | [InChI]
1S/C24H28FN3O2.ClH/c1-26-18-28(21-6-3-2-4-7-21)24(23(26)30)13-16-27(17-14-24)15-5-8-22(29)19-9-11-20(25)12-10-19;/h2-4,6-7,9-12H,5,8,13-18H2,1H3;1H | [InChIKey]
OGOQOKYYPNFSOL-UHFFFAOYSA-N | [SMILES]
Cl.CN1CN(c2ccccc2)C3(CCN(CCCC(=O)c4ccc(F)cc4)CC3)C1=O |
| Hazard Information | Back Directory | [Uses]
Reference standard. | [Definition]
ChEBI: N-Methylspiperone is an aromatic ketone. | [General Description]
N-Methylspiperone acts as a D2?dopamine receptor antagonist. It is an analog of spiperone. The isotope 3-N-[11C]methylspiperone ([11C]NMSP) is widely used in dopamine receptor imaging in positron emission tomography (PET). | [Biochem/physiol Actions]
D2 dopamine receptor antagonist. | [IC 50]
D2 Receptor |
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