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875910-01-3

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875910-01-3 Structure

875910-01-3 Structure
IdentificationBack Directory
[Name]

AGA-(C8R) HNG17, Humanin derivative
[CAS]

875910-01-3
[Synonyms]

PAGASRLLLLTGEIDLP
AGA-(C8R) HNG17, Humanin derivative
L-Proline, L-prolyl-L-alanylglycyl-L-alanyl-L-seryl-L-arginyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-threonylglycyl-L-α-glutamyl-L-isoleucyl-L-α-aspartyl-L-leucyl-
[Molecular Formula]

C78H134N20O24
[MDL Number]

MFCD09842373
[MOL File]

875910-01-3.mol
[Molecular Weight]

1736.05
Chemical PropertiesBack Directory
[density ]

1.41±0.1 g/cm3(Predicted)
[pka]

3.42±0.20(Predicted)
Hazard InformationBack Directory
[Uses]

AGA-(C8R) HNG17, Humanin derivative is a potent humanin (HN) derivative. AGA-(C8R) HNG17, Humanin derivative completely suppresses neuronal cell death by Alzheimer's disease-relevant insults[1].
[References]

[1] Chiba T, et al. Development of a femtomolar-acting humanin derivative named colivelin by attaching activity-dependent neurotrophic factor to its N terminus: characterization of colivelin-mediated neuroprotection against Alzheimer's disease-relevant insults in vitro and in vivo. J Neurosci. 2005 Nov 2;25(44):10252-61. DOI:10.1523/JNEUROSCI.3348-05.2005
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