| Identification | Back Directory | [Name]
6H-Furo[2',3':4,5]oxazolo[3,2-a]pyriMidin-6-one, 2-azido-2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxyMethyl)-, (2R,3S,3aS,9aR)- | [CAS]
876707-99-2 | [Synonyms]
CS-M1995
Nucleoside-Analog-1
Nucleoside Analog 1,NucleosideAnalog1
6H-Furo[2',3':4,5]oxazolo[3,2-a]pyriMidin-6-one, 2-azido-2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxyMethyl)-, (2R,3S,3aS,9aR)- | [Molecular Formula]
C9H9N5O5 | [MDL Number]
MFCD23160110 | [MOL File]
876707-99-2.mol | [Molecular Weight]
267.198 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
11.597±0.40(predicted) | [color ]
White to off-white | [Water Solubility ]
Water : 20 mg/mL (74.85 mM) |
| Hazard Information | Back Directory | [Description]
Nucleoside-Analog-1 is a 4′-Azidocytidine analogue against Hepatitis C virus replication. | [Uses]
Nucleoside-Analog-1 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [storage]
Store at -20°C | [References]
[1]. Smith DB, et al. The design, synthesis, and antiviral activity of 4'-azidocytidine analogues against hepatitis C virus replication: the discovery of 4'-azidoarabinocytidine. J Med Chem. 2009 Jan 8;52(1):219-23. [2]. Smith DB, et al. The design, synthesis, and antiviral activity of monofluoro and difluoro analogues of 4'-azidocytidine against hepatitis C virus replication: the discovery of 4'-azido-2'-deoxy-2'-fluorocytidine and 4'-azido-2'-dideoxy-2',2'-difluorocytidine. J Med Chem. 2009 May 14;52(9):2971-8. |
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| Company Name: |
SPIRO PHARMA
|
| Telephone: |
|
| Website: |
www.spiropharma.com.cn |
| Company Name: |
NewCan Biotech Limited
|
| Telephone: |
+86-571-86912261 19975279805 |
| Website: |
https://www.newcanbio.com/ |
|