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876707-99-2

876707-99-2 Structure

876707-99-2 Structure
IdentificationBack Directory
[Name]

6H-Furo[2',3':4,5]oxazolo[3,2-a]pyriMidin-6-one, 2-azido-2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxyMethyl)-, (2R,3S,3aS,9aR)-
[CAS]

876707-99-2
[Synonyms]

CS-M1995
Nucleoside-Analog-1
Nucleoside Analog 1,NucleosideAnalog1
6H-Furo[2',3':4,5]oxazolo[3,2-a]pyriMidin-6-one, 2-azido-2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxyMethyl)-, (2R,3S,3aS,9aR)-
[Molecular Formula]

C9H9N5O5
[MDL Number]

MFCD23160110
[MOL File]

876707-99-2.mol
[Molecular Weight]

267.198
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[form ]

Solid
[color ]

White to off-white
[Water Solubility ]

Water : 20 mg/mL (74.85 mM)
Hazard InformationBack Directory
[Description]

Nucleoside-Analog-1 is a 4′-Azidocytidine analogue against Hepatitis C virus replication.

[Uses]

Nucleoside-Analog-1 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
[storage]

Store at -20°C
[References]

[1]. Smith DB, et al. The design, synthesis, and antiviral activity of 4'-azidocytidine analogues against hepatitis C virus replication: the discovery of 4'-azidoarabinocytidine. J Med Chem. 2009 Jan 8;52(1):219-23. [2]. Smith DB, et al. The design, synthesis, and antiviral activity of monofluoro and difluoro analogues of 4'-azidocytidine against hepatitis C virus replication: the discovery of 4'-azido-2'-deoxy-2'-fluorocytidine and 4'-azido-2'-dideoxy-2',2'-difluorocytidine. J Med Chem. 2009 May 14;52(9):2971-8.

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