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IdentificationBack Directory
[Name]

3-(trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one
[Synonyms]

Sitagliptin Impurity 114
3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3- a]pyrazin-8-one
3-(trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one
1,2,4-Triazolo[4,3-a]pyrazin-8(5H)-one, 6,7-dihydro-3-(trifluoromethyl)-
[MDL Number]

MFCD24609250
[Molecular Weight]

206.13
Chemical PropertiesBack Directory
[density ]

1.90±0.1 g/cm3(Predicted)
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

Off-White to Light Grey
Hazard InformationBack Directory
[Uses]

3-(Trifluoromethyl)-6,7-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-8(5H)-one is an intermediate in the synthesis of Sitagliptin Triazecine Analog (S491015). Sitagliptin Triazecine Analog is related to the family of Sitagliptin compounds which has recently been approved for the therapy of type II diabetes.
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