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879551-04-9

879551-04-9 Structure

879551-04-9 Structure
IdentificationBack Directory
[Name]

(3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyl-dihydrofuran-2(3H)-one
[CAS]

879551-04-9
[Synonyms]

-3-methyldihydrofuran-2(3H)
-3-Fluoro-4-hydroxy-5-(hydroxymethyl)
D-erythro-Pentonic acid, 2-deoxy-2-fluoro-2-methyl-, |-lactone
(3R,4R,5R)-3-FLUORO-4-HYDROXY-5-(HYDROXYMETHYL)-3-METHYL-DIHYD
D-erythro-Pentonic acid, 2-deoxy-2-fluoro-2-methyl-, gamma-lactone
(2R)-2-Deoxy-2-fluoro-2-methyl-D-erythro-pentonic acid gamma-lactone
(3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyloxolan-2-one
D-erythro-Pentonic acid, 2-deoxy-2-fluoro-2-methyl-, γ-lactone, (2R)-
(4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyldihydrofuran-2(3H)-one
(3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyl-tetrahydrofuran-2-one
(3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyl-dihydrofuran-2(3H)-one
(3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyl-dihydrofuran-2(3H)-one USP/EP/BP
[Molecular Formula]

C6H9FO4
[MDL Number]

MFCD23106443
[MOL File]

879551-04-9.mol
[Molecular Weight]

164.132
Chemical PropertiesBack Directory
[Melting point ]

142-143℃ (ethyl acetate heptane )
[Boiling point ]

352.7±42.0 °C(Predicted)
[density ]

1.42±0.1 g/cm3(Predicted)
[storage temp. ]

Inert atmosphere,2-8°C
[pka]

11.46±0.60(Predicted)
[Appearance]

Off-white to light brown Solid
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H320-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

(3R,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyldihydrofuran-2(3H)-one can be used for synthetic preparation for asymmetric synthesis of dibenzoyl fluoro methyl-D-ribono-γ-lactone via asymmetric aldol condensation and enzymic hydrolysis from isopropylidene-D-glyceraldehyde and Et fluoropropionate.
[Synthesis]

Chlorination or acylation of trans-5-hydroxy-1,3-oxathiolane-2-carboxylic acid-L menthol ester and coupling with cytosine and 5-fluorocytosine or with silicone-protected cytosine and 5-fluorocytosine. -The process of chlorination or acylation requires hig
Spectrum DetailBack Directory
[Spectrum Detail]

(3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxyMethyl)-3-Methyl-dihydrofuran-2(3H)-one(879551-04-9)1HNMR
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