ChemicalBook--->CAS DataBase List--->879564-86-0

879564-86-0

879564-86-0 Structure

879564-86-0 Structure
IdentificationBack Directory
[Name]

ANTI-AMYLOID, BETA
[CAS]

879564-86-0
[Synonyms]

Anti-PN2
Anti-AAA
Anti-AD1
Anti-ABPP
Anti-APPI
Anti-CVAP
ANTI-ABETA
Rhodblock 3
Clone BAM91
Anti-CTFgamma
ANTI-BETA AMYLOID
ANTI-AMYLOID, BETA
Anti-AMYLOID BETA A4
Anti-A4 AMYLOID PROTEIN
ANTI-HUMAN BETA AMYLOID
ANTI-AMYLOID BETA-PEPTIDE
ANTI-BETA-AMYLOID PROTEIN
ANTI-BETA-AMYLOID RABBIT PAB
ANTI-PAN BETA-AMYLOID, HUMAN
MONOCLONAL ANTI-BETA-AMYLOID
Anti-AMYLOID-BETA PROTEIN (ABP)
Rhodblock 3 >=98% (HPLC), powder
ANTI-PAN BETA-AMYLOID, HUMAN (RABBIT)
ANTI-PAN BETA-AMYLOID (15-30) RABBIT PAB
3-Benzofuranacetamide, 5-chloro-6-methyl-
Anti-APP (ab2) antibody produced in rabbit
PAN BETA-AMYLOID (AB-1) POLYCLONAL ANTIBODY
Anti-amyloid beta A4 protein precursor, AAA
2-(5-Chloro-6-methylbenzofuran-3-yl)-acetamide
Anti-A-BETA, Anti-Amyloid β Precursor Protein
Anti-APP (N-terminal region) antibody produced in rabbit
Monoclonal Anti-β-Amyloid antibody produced in mouse
Anti-Amyloid β (A4) precursor protein (protease nexin-II, Alzheimer disease)
Anti-Amyloid β (A4) precursor protein (peptidase nexin-II, Alzheimer disease)
[Molecular Formula]

C11H10ClNO2
[MDL Number]

MFCD06771404
[MOL File]

879564-86-0.mol
[Molecular Weight]

223.66
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[solubility ]

DMSO: ≥50mg/mL
[form ]

buffered aqueous solution
[color ]

white to off-white
[biological source]

rabbit
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

22
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

The antibody is useful in immunohistochemistry, immunoblotting, ELISA, and competitive ELISA. Also, this antibody has been used to neutralize Aβ assemblies in brains of transgenic mice expressing a mutant form of amyloid precursor protein, and for in vivo deep tissue imaging using near-IR optical spectrum.
[General Description]

The antibody reacts specifically with β-amyloid protein. The epitope recognized by the antibody resides within amino acids 1-12 of the β-amyloid protein. It specifically stains amyloid plaques within the cortex and amyloid deposits in blood vessels using formic acid-treated, formalin-fixed, paraffin-embedded, and Methacarn-fixed sections of human Alzheimer′s disease (AD) brain tissue.
[Biochem/physiol Actions]

β-amyloid gene acts as the substrate of insulin-degrading enzyme (IDE). It plays a major role in the pathogenesis of Alzheimer′s disease (AD) and type 2 diabetes mellitus (DM2).
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