| Identification | Back Directory | [Name]
Dulaglutide | [CAS]
879600-73-4 | [Synonyms]
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(furan-2-yl)imidazo[1,2-a]pyridin-3-amine
Imidazo[1,2-a]pyridin-3-amine, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(2-furanyl)- | [Molecular Formula]
C19H15N3O3 | [MOL File]
879600-73-4.mol | [Molecular Weight]
333.34 |
| Hazard Information | Back Directory | [Description]
Dulaglutide is a once-weekly, GLP-1 receptor agonist, consisting of a DPP-IV-protected GLP-1 analogue covalently linked to a human IgG4-Fc heavy chain by a small peptide linker,thereby protecting the GLP-1 moiety from inactivation by dipeptidyl peptidase.
| [Clinical Use]
Long-acting glucagon-like peptide 1 (GLP-1) receptor
agonist:
Treatment of type 2 diabetes mellitus | [Side effects]
The most common seen being transient and mild GI side effects. These include nausea, vomiting, and diarrhea which are expected based upon the mechanism of action and usually decrease over time. | [Drug interactions]
Potentially hazardous interactions with other drugs
None known | [Metabolism]
Dulaglutide is presumed to be degraded into its
component amino acids by general protein catabolism
pathways. |
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Aobolihui
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