| Identification | Back Directory | [Name]
DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE | [CAS]
881-95-8 | [Synonyms]
Methoxyadrenaline
METANEPHRINE (HCL)
DL-MetanephrineHCl
Epinephrine Impurity 29
METANEPHRINE HYDROCHLORIDE
Metanephrine HCl (solution)
Metadrenaline Hydrochloride
DL-METANEPHRINE HYDROCHLORIDE
Metanephrine hydrochloride salt
Metanephrine Hydrochloride (Rac)
3-methoxy-adrenalinhydrochloride
(+/-)-Metanephrine hydrochloride
Metanephrine 13C D3 hydrochloride
DL-MetanephrineCl (not deuterated)
m-O-Methyladrenaline hydrochloride
D,L-Metanephrine hydrochloride salt
DL-3-O-Methyladrenaline hydrochloride
DL-M-O-METHYLEPINEPHRINE HYDROCHLORIDE
METANEPHRINE HYDROCHLORIDE >97% REFERENC E STD. FOR CH
α-[(MethylaMino)Methyl]-vanillyl Alcohol Hydrochloride
alpha-((methylamino)methyl)-vanillylalcohohydrochloride
rac Metanephrine Hydrochloride Salt (0.1mg/mL in Methanol)
(+/-)-alpha-[(Methylamino)methyl]vanillyl alcohol hydrochloride
(.+-)-alpha-[(methylamino)methyl]vanillyl alcohol hydrochloride
4-[1-hydroxy-2-(methylamino)ethyl]-2-methoxyphenol hydrochloride
4-[1-hydroxy-2-(methylamino)ethyl]-2-methoxy-phenol hydrochloride
4-Hydroxy-3-Methoxy-α-[(MethylaMino)Methyl]benzeneMethanol Hydrochloride
4-HYDROXY-3-METHOXY-ALPHA-(METHYLAMINOMETHYL)BENZYL ALCOHOL HYDROCHLORIDE
4-hydroxy-3-methoxy-alpha-((methylamino)methyl)-benzenemethanohydrochlorid
4-HYDROXY-3-METHOXY-ALPHA-[METHYLAMINOMETHYL]BENZENE-METHANOL HYDROCHLORIDE
(+-)-4-hydroxy-3-methoxy-alpha-((methylamino)methyl)benzenemethanolhydrochlo
DL-m-O-Methylepinephrine hydrochloride, 4-Hydroxy-3-methoxy-α-(methylaminomethyl)benzene-methanol hydrochloride | [EINECS(EC#)]
212-922-2 | [Molecular Formula]
C10H16ClNO3 | [MDL Number]
MFCD00012487 | [MOL File]
881-95-8.mol | [Molecular Weight]
233.69 |
| Chemical Properties | Back Directory | [Melting point ]
180-182?C | [density ]
1.320 g/cm3 | [storage temp. ]
-20°C Freezer | [solubility ]
H2O: soluble
| [form ]
powder
| [color ]
white to off-white
|
| Hazard Information | Back Directory | [Chemical Properties]
Off-White to Pale Yellow Solid | [Uses]
A metabolite of Epinephrine (E588585). A naturraly occurring derivative of Epinephrine, found in urine and in certain tissues. | [Biochem/physiol Actions]
Metanephrine is an endogenous metabolite of ephinephrine, formed by catechol-O-methyl transferase activity. It is best known as a biomarker for cancers, as levels of free metanephrine are used to diagnose pheochromocytoma. Metanephrine was previously thought to be biologically inactive, but it is a more potent agonist at Trace amine associated receptor TAAR1 than either epinephrine or norepinephrine. Trace amine associated receptors (TAARs) are recently discovered GPCRs that are activated by endogenous trace amines (tyramine, tryptamine, synephrine, octopamine, β-phenylethylamine), which are chemically similar to monoaminergic neurotransmitters (epinephrine, norepinephrine, dopamine). Trace amines and TAARs are expressed in brain and are implicated in modulation of monoaminergic neurotransmission. |
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