| Identification | Back Directory | [Name]
platelet factor 4 (59-70) | [CAS]
88145-47-5 | [Synonyms]
platelet factor 4 (59-70)
L-Serine, N-[N-[N-[N-[N2-[N2-[N-[N-[N2-[N2-(N-L-leucyl-L-tyrosyl)-L-lysyl]-L-lysyl]-L-isoleucyl]-L-isoleucyl]-L-lysyl]-L-lysyl]-L-leucyl]-L-leucyl]-L-α-glutamyl]- (9CI) | [Molecular Formula]
C71H126N16O17 | [MOL File]
88145-47-5.mol | [Molecular Weight]
1475.86 |
| Chemical Properties | Back Directory | [Boiling point ]
1666.7±65.0 °C(Predicted) | [density ]
1.192±0.06 g/cm3(Predicted) | [pka]
2.95±0.10(Predicted) | [Sequence]
Leu-Tyr-Lys-Lys-Ile-Ile-Lys-Lys-Leu-Leu-Glu-Ser |
| Hazard Information | Back Directory | [Description]
Platelet factor 4 (59-70) elicits human neutrophil & monocyte chemotaxis. | [Uses]
Platelet factor 4 (59-70) is a polypeptide, which is composed of platelets and megakaryocytes. Platelet factor 4 (59-70) stimulates dog mastocytoma cells, promotes the release of histamine and leukotrienes[1]. | [References]
[1] Goetzl EJ, et al., Stimulus specificity of the generation of leukotrienes by dog mastocytoma cells. J Exp Med. 1983 Sep 1;158(3):731-7. DOI:10.1084/jem.158.3.731 |
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