| Identification | Back Directory | [Name]
N6-(Aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide cyclic (16)-disulfide acetate | [CAS]
881997-86-0 | [Synonyms]
Eptifibatide.XAcOH
Eptifibatide xAcetate
Eptifibatide acetate >=98% (HPLC)
Cyclo(S,S)-Mpr(Har)GDWPC-NH2 acetate
Eptifibatide acetate (148031-34-9 free base)
Eptifibatide acetate (148031 34 9 free base),Eptifibatide acetate (148031349 free base)
N6-(Aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide cyclic (16)-disulfide acetate
N6-(Aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-α-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide cyclic (16)-disulfide acetate
2-((3R,11S,17S,20S,25aS)-20-((1H-Indol-3-yl)methyl)-3-carbamoyl-11-(4-guanidinobutyl)-1,9,12,15,18,21-hexaoxodocosahydro-7H-pyrrolo[2,1-g][1,2]dithia[5,8,11,14,17,20]hexaazacyclotricosin-17-yl)acetic acid acetic acid (1:x) | [Molecular Formula]
C37H53N11O11S2 | [MDL Number]
MFCD08690339 | [MOL File]
881997-86-0.mol | [Molecular Weight]
892.02 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
H2O: soluble2mg/mL, clear (warmed) | [form ]
powder | [color ]
white to beige | [Water Solubility ]
H2O: 2mg/mL, clear (warmed) |
| Hazard Information | Back Directory | [Uses]
The acetate salt form of eptifibatide (E592000), an arginine-glycine-aspartate-mimetic which reversibly binds to platelets to reduce the risk of cardiac ischemic events. | [General Description]
Eptifibatide acetate is a cyclic heptapeptide. It is the member of the class arginin-glycin-aspartat-mimetics. Eptifibatide has a short half-life. The drug decreases the risk of myocardial infarction (MI). Eptifibatide acetate might be associated with thrombocytopenia. | [Biochem/physiol Actions]
Eptifibatide is a specific inhibitor of fibrinogen binding to the platelet membrane integrin glycoprotein GPIIb/IIIa receptor, preventing platelet aggregation. Eptifibatide binds reversibly and competitively. |
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