| Identification | Back Directory | [Name]
oxy-Arachidonoyl Ethanolamide Exclusive | [CAS]
883296-70-6 | [Synonyms]
oxy-Arachidonoyl Ethanolamide Exclusive
(5Z,8Z,11Z,14Z)-N-(2-hydroxyethoxy)icosa-5,8,11,14-tetraenamide | [Molecular Formula]
C22H37NO3 | [MDL Number]
MFCD09951894 | [MOL File]
883296-70-6.mol | [Molecular Weight]
363.53 |
| Chemical Properties | Back Directory | [density ]
0.966±0.06 g/cm3(Predicted) | [solubility ]
DMF: 1 mg/ml; DMSO: 1 mg/ml; Ethanol: 25 mg/ml; Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml | [pka]
14.33±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
AEA acts as an endogenous mimic of Δ9-THC, the psychotropic component of marijuana. oxy-AEA is the O-alkyl-N-acyl oxyhomologue of AEA. oxy-AEA is selective for the peripheral cannabinoid (CB2) receptor with Ki values of 0.47 and 0.081 μM for hCB1 and hCB2, respectively. In comparison, AEA has a greater affinity for the central cannabinoid (CB1) receptor with Ki values of 0.07 and 0.18 μM for hCB1 and hCB2, respectively. oxy-AEA is the first known fatty acid amide with a reversed CB1/CB2 affinity ratio. | [Uses]
oxy-Arachidonoyl ethanolamide (O-alkyl-N-acylhydroxylamine) is an O-alkyl-N-acyl oxime derivative[1]. | [Definition]
ChEBI: Oxy-Arachidonoyl Ethanolamide is a primary alcohol. | [References]
[1] Sultan Mayar, et al. Examining Changes in Gramicidin Current Induced by Endocannabinoids. bioRXiv. 2024.11.05.622072. |
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