| Identification | Back Directory | [Name]
CLOMIFENE CITRATE | [CAS]
88431-47-4 | [Synonyms]
CLOMID
CLOMOXIR
CLOMPHID
PERGOTIME
SEROPHENE
CLOMIPHENE CITRATE
CLOMIPHENE CITRATE SALT
Clomiphene Citrate 88431-47-4
2-[5-(4-Chlorophenyl)pentyl]oxirane-2-carboxylic acid
2-Oxiranecarboxylic acid, 2-[5-(4-chlorophenyl)pentyl]-
2-[4-(2-CHLORO-1,2-DIPHENYLETHENYL)-PHENOXY]-N,N-DIETHYLETHANAMINE CITRATE SALT | [EINECS(EC#)]
200-035-3 | [Molecular Formula]
C32H36ClNO8 | [MDL Number]
MFCD00058322 | [MOL File]
88431-47-4.mol | [Molecular Weight]
598.08 |
| Hazard Information | Back Directory | [Uses]
2-[5-(4-Chlorophenyl)pentyl]oxirane-2-carboxylic acid can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes. | [General Description]
Clomiphene citrate, 2-[4(2-chloro-1,2-diphenylethenyl)phenoxy]-N,N-diethylethanamine(Clomid), is used as an ovulation stimulant inwomen desiring pregnancy. Although early literature refersto clomiphene as an estrogen antagonist, it is more accuratelya SERM. Clomiphene is chemically a mixture of two geometricisomers, zuclomiphene, the cis-isomer, and enclomiphene,the trans-isomer. In animal studies, these isomershave different estrogenic actions in different tissues.Zuclomiphene appears to have weak agonist actions on alltissues studied, whereas enclomiphene has antagonist actionson uterine tissue, but agonist action on bone tissue. The actionsof clomiphene in humans are likely a composite of theactions of the two isomers. |
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