| Identification | Back Directory | [Name]
Stannane, (4-chloro-1-methylenebutyl)trimethyl- | [CAS]
89045-21-6 | [Synonyms]
Stannane, (4-chloro-1-methylenebutyl)trimethyl- | [Molecular Formula]
C8H17ClSn | [MOL File]
89045-21-6.mol | [Molecular Weight]
267.384 |
| Hazard Information | Back Directory | [Uses]
Stannane, (4-chloro-1-methylenebutyl)trimethyl- is used for cyclohexane annulation; bifunctional reagent; intramolecular Stille coupling.
| [Synthesis]
Stannane, (4-chloro-1-methylenebutyl)trimethyl- is synthesized by treatment of commercially available 5-chloro-1-pentyne with Me3SnCu.Me2S in THF at -68 °C in the presence of excess MeOH provides a 9:1 mixture of 5-chloro-2-trimethylstannyl-1-pentene and 5-chloro-1-trimethylstannyl-1-pentene.6-8 Slow column chromatography removes the minor product.
| [storage]
Stannane, (4-chloro-1-methylenebutyl)trimethyl- should be considered as toxic compounds. This reagent should be handled in a well-ventilated fume hood and gloves should be worn to prevent contact with the skin.
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