ChemicalBook--->CAS DataBase List--->89196-95-2

89196-95-2

Request For Quotation
89196-95-2 Structure

89196-95-2 Structure
IdentificationBack Directory
[Name]

2-(2-BENZOFURANYL)-2-IMIDAZOLINE HYDROCHLORIDE
[CAS]

89196-95-2
[Synonyms]

2-BFI HCL
2-BFI HYDROCHLORIDE
2-BFI hydrochlorid (2 BFI hydrochloride
2-(2-BENZOFURANYL)-2-IMIDAZOLINE HYDROCHLORIDE
2-(Benzofuran-2-yl)-2-imidazoline Hydrochloride
[Molecular Formula]

C11H11ClN2O
[MDL Number]

MFCD00672666
[MOL File]

89196-95-2.mol
[Molecular Weight]

222.67
Chemical PropertiesBack Directory
[storage temp. ]

Desiccate at RT
[solubility ]

DMSO: 20mg/mL, clear
[form ]

White powder.
[color ]

White to off-white
[Water Solubility ]

Soluble to 100 mM in water
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501
Hazard InformationBack Directory
[Uses]

2-(Benzofuran-2-yl)-2-imidazoline Hydrochloride is a I2 receptor agonists that induces hypothermic effect in rats.
[Biological Activity]

High affinity I 2 ligand (K i = 9.8 nM). Putative I 2 agonist; potentiates morphine antinociception. Produces ipsiversive rotational behavior in rats with a full 6-OHDA lesion of the nigrostriatal tract.
[in vivo]

RX 801077 hydrochloride (5, 10, 20 mg/kg; i.p.; twice daily for 3 days) inhibits NLRP3 inflammasome-induced inflammation and necroptosis in a rat model of traumatic brain injury[2].

Animal Model:280-300 g, Male adult Sprague-Dawley rats (TBI model)[2]
Dosage:5, 10, 20 mg/kg
Administration:I.p.; twice daily for 3 days
Result:Attenuated neurological deficits, brain edema, BBB permeability and cortical tissue loss in a rat model of TBI, reduced microglial activation, neutrophil infiltration, and proinflammatory cytokine IL-1β secretion, reduced the expression of RIP1 and RIP3 in neurons in the pericontusional cortex.
[storage]

Desiccate at RT
Spectrum DetailBack Directory
[Spectrum Detail]

2-(2-BENZOFURANYL)-2-IMIDAZOLINE HYDROCHLORIDE(89196-95-2)1HNMR
89196-95-2 suppliers list
Company Name: J & K SCIENTIFIC LTD.  
Telephone: 18210857532 18210857532
Website: https://www.jkchemical.com
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Telephone: 18930552037
Website: www.chemicalbook.com/showsupplierproductslist13285/0_en.htm
Company Name: Bide Pharmatech Ltd.  
Telephone: 400-164-7117 18317119277
Website: www.bidepharm.com
Company Name: Shanghai Lollane Biological Technology Co.,Ltd.  
Telephone: 021-52996696，15000506266 15000506266
Website: http://www.bioll.com
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Telephone: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Telephone: 15026964105
Website: www.shyuanye.com
Company Name: Tianjin Kailiqi Biotechnology Co., Ltd.  
Telephone: 15076683720
Website: http://www.cw-bio.com
Company Name: ShangHai Biochempartner Co.,Ltd  
Telephone: 177-54423994 17754423994
Website: www.biochempartner.com
Company Name: Shanghai Chaolan Chemical Technology Center  
Telephone: QQ：65489617 13301690235
Website: www.atkchemical.com/
Company Name: Shenzhen Polymeri Biochemical Technology Co., Ltd.  
Telephone: +86-400-002-6226
Website: https://www.rrkchem.com
Company Name: Career Henan Chemica Co  
Telephone: +86-0371-86658258 +86-13203830695
Website: www.coreychem.com/
Company Name: Changzhou Chenhong Biotechnology Co., Ltd.  
Telephone: +86-0519-85788828 +86-13775037613
Website: http://www.chemrenblock.com/
Company Name: Suzhou Chenrui Biotechnology Co. LTD  
Telephone: 17625585511
Website: www.chemicalbook.com/ShowSupplierProductsList660257/0_EN.htm
Company Name: MedBioPharmaceutical Technology Inc  
Telephone: 021-69568360 18916172912
Website: http://www.med-bio.cn/
Company Name: Energy Chemical  
Telephone: 021-58432009 400-005-6266
Website: http://www.energy-chemical.com
Company Name: Beijing Jin Ming Biotechnology Co., Ltd.  
Telephone: 010-60605840
Website: http://www.jm-bio.com/
Company Name: Shanghai Universal Biotech Co.,Ltd  
Telephone: 15921930842 15921930842
Website: www.univ-bio.com/
Company Name: Bide Pharmatech Ltd.  
Telephone: 400-1647117 13681763483
Website: https://www.bidepharm.com/
Tags:89196-95-2 Related Product Information