| Identification | Back Directory | [Name]
acetic acid:(3S)-3-[[(2S)-6-amino-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]-4-[[(2S)-1-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid | [CAS]
89318-88-7 | [Synonyms]
acetic acid:(3S)-3-[[(2S)-6-amino-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]-4-[[(2S)-1-[[(1S)-1-carboxy-2-(4-hydroxyphenyl)ethyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid | [Molecular Formula]
C32H53N9O11 | [MDL Number]
MFCD00133107 | [MOL File]
89318-88-7.mol | [Molecular Weight]
739.817 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C, away from moisture and light | [solubility ]
Soluble in DMSO | [form ]
Solid | [color ]
White to off-white | [Sequence]
Arg-Lys-Asp-Val-Tyr |
| Hazard Information | Back Directory | [Uses]
Thymopentin acetate is a biologically active peptide secreted mainly by the epithelial cells of thymic cortex and medulla. Thymopentin acetate is an effective immunomodulatory agent with a short plasma half-life of 30 seconds. Thymopentin acetate enhances the generation of T-cell lineage derived from human embryonic stem cells (hESCs)[1][2]. | [storage]
-20°C, away from moisture and light | [References]
[1] Zhu MX, et al. Thymopentin enhances the generation of T-cell lineage derived from human embryonic stem cells in vitro. Exp Cell Res. 2015 Feb 15;331(2):387-98. DOI:10.1016/j.yexcr.2014.12.012
[2] Lin S, et al. Novel strategy for immunomodulation: Dissolving microneedle array encapsulating thymopentin fabricated by modified two-step molding technology. Eur J Pharm Biopharm. 2018 Jan;122:104-112. DOI:10.1016/j.ejpb.2017.10.011 |
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