| Identification | Back Directory | [Name]
4-QuinazolinaMine, N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-Methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-, (2E)-2-butenedioate (1:2) | [CAS]
893428-72-3 | [Synonyms]
Saracatinib Fumarate
Saracatinib difuMarate
AZD 0530 difumarate - Saracatinib
N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-Methyl-1-piperazinyl)ethoxy]-5-(tetrahydro-2H-pyran-4-yloxy)-4-quinazolinaMine (2E)-2-butenedioate (1:2)
4-QuinazolinaMine, N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-Methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-, (2E)-2-butenedioate (1:2) | [EINECS(EC#)]
641-395-5 | [Molecular Formula]
C31H36ClN5O9 | [MDL Number]
MFCD12546336 | [MOL File]
893428-72-3.mol | [Molecular Weight]
658.11 |
| Hazard Information | Back Directory | [Uses]
Saracatinib (AZD0530) difumarate is a potent Src inhibitor with IC50 values of 2.7-11 nM for c-Src, Lck, c-YES, Lyn, Fyn, Fgr and Blk, and is selective for other tyrosine kinases. [1]. | [References]
[1] Green TP, et al. Preclinical anticancer activity of the potent, oral Src inhibitor AZD0530. Mol Oncol, 2009, 3(3), 248-261. DOI:10.1016/j.molonc.2009.01.002 |
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