| Identification | Back Directory | [Name]
aprikalim | [CAS]
89544-10-5 | [Synonyms]
RP-49356
aprikalim
N-Methyl-2-(3-pyridyl)tetrahydrothiopyran-2-carbothioamide-1-oxide
N-Methyl[tetrahydro-2-(3-pyridyl)-2H-thiopyran]-2-carbothioamide 1-oxide
N-Methyl-[tetrahydro-2-(3-pyridinyl)-2H-thiopyran]-2-carbothioamide 1-oxide
2-(Methylaminocarbonothioyl)-2-(3-pyridinyl)-tetrahydro-2H-thiopyran 1-oxide
2H-Thiopyran-2-carbothioamide, tetrahydro-N-methyl-2-(3-pyridinyl)-, 1-oxide | [MOL File]
89544-10-5.mol |
| Hazard Information | Back Directory | [Uses]
rel-Aprikalim (rel-RP 52891) is the relative configuration of Aprikalim (HY-121183). Aprikalim (RP 52891), a potassium channel opener (KCO), activates ATP-sensitive K+ (KATP) channels in guinea pig ventricular myocytes[1]. | [References]
[1] D Thuringer, et al. Time-dependent fading of the activation of KATP channels, induced by aprikalim and nucleotides, in excised membrane patches from cardiac myocytes. Br J Pharmacol. 1995 May;115(1):117-27. DOI:10.1111/j.1476-5381.1995.tb16328.x |
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