| Identification | Back Directory | [Name]
thiotropocin | [CAS]
89550-93-6 | [Synonyms]
thiotropocin
4-Hydroxy-8-thioxocyclohept[c][1,2]oxathiol-3(8H)-one
Cyclohept[c][1,2]oxathiol-3(8H)-one, 4-hydroxy-8-thioxo- | [Molecular Formula]
C8H4O3S2 | [MDL Number]
MFCD01734410 | [MOL File]
89550-93-6.mol | [Molecular Weight]
212.25 |
| Hazard Information | Back Directory | [Description]
Thiotropocin is a sulfur-containing 7-membered-ring antibiotic. | [Uses]
Thiotropocin is a tropothione Antibiotic with antibacterial activities against Gram-positive and Gram-negative bacteria, some phytopathogens and mycoplasma. Thiotropocin causes morphological changes of Proteus mirabilis and Escherichia coli[1]. | [Definition]
ChEBI: Thiotropocin is a thiocarbonyl compound that is 3,8-dihydrocyclohepta[c][1,2]oxathiole substituted at positions 3, 4 and 8 by oxo, hydroxy, and thiocarbonyl groups, respectively. It is an antibiotic first isolated in 1984 from the fermentation broth of Pseudomonas sp. CB104. It has a role as an antibacterial agent, a bacterial metabolite and a marine metabolite. It is an organic hydroxy compound, a thiocarbonyl compound, an organic heterobicyclic compound, a thionoester and an organosulfur heterocyclic compound. It is a tautomer of a tropodithietic acid. | [References]
[1] Kintaka K, et al. Thiotropocin, a new sulfur-containing 7-membered-ring antibiotic produced by a Pseudomonas sp. J Antibiot (Tokyo). 1984 Nov;37(11):1294-300. DOI:10.7164/antibiotics.37.1294 |
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