| Identification | Back Directory | [Name]
Silane, trimethyl-2-propenyl-, zinc complex | [CAS]
89822-47-9 | [Synonyms]
Silane, trimethyl-2-propenyl-, zinc complex
Chloro[1-[(trimethylsilyl)methyl]ethenyl]zinc
Zinc, chloro[1-[(trimethylsilyl)methyl]ethenyl]- | [Molecular Formula]
C6H13ClSiZn | [MOL File]
89822-47-9.mol | [Molecular Weight]
214.085 |
| Hazard Information | Back Directory | [Uses]
Spiro-γ-lactone Synthesis via Reactions with Carbonyl
Compounds.
Although lithiated allyltrimethylsilane adds to
simple ketones with good regioselectivity (eq 1),its addition to
17-ketosteroids produces a mixture of α and γ adducts. Transmetalation
of allyltrimethylsilyllithium with ZnCl2 leads to a reagent
(allyltrimethylsilylzinc chloride) which adds with complete regioselectivity.
to this type of hindered ketone.
| [Preparation]
deprotonation of allyltrimethylsilane
with n-butyllithium in THF at ?78°C or s-butyllithium in
THF/TMEDA, followed by the addition of zinc chloride.
The reagent is prepared in situ and used directly. |
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