| Identification | Back Directory | [Name]
Benzoic acid, 3-((4-(3-cyclohexyl-3-hydroxy-1-propenyl)hexahydro-5-hyd roxy-2(1H)-pentalenylidene)methyl)-, (2E,3aalpha,4alpha(1E,3R*),5beta, 6aalpha)-(+-)- | [CAS]
89955-40-8 | [Synonyms]
Cg 4305
OINUMRGCICIETD-CGKNXJIZSA-N
Benzoic acid, 3-((4-(3-cyclohexyl-3-hydroxy-1-propenyl)hexahydro-5-hyd roxy-2(1H)-pentalenylidene)methyl)-, (2E,3aalpha,4alpha(1E,3R*),5beta, 6aalpha)-(+-)- | [Molecular Formula]
C25H32O4 | [MOL File]
89955-40-8.mol | [Molecular Weight]
396.52 |
| Chemical Properties | Back Directory | [Boiling point ]
596.4±50.0 °C(Predicted) | [density ]
1.262±0.06 g/cm3(Predicted) | [solubility ]
DMF: 5 mg/ml
DMSO: 10 mg/ml
DMSO: PBS (pH 7.2) (1:10): 0.1 mg/ml
Ethanol: 3 mg/ml | [pka]
4.17±0.10(Predicted) |
| Hazard Information | Back Directory | [Description]
CG 4305 is a stable carbacyclic analog of PGI2 that inhibits ADP-induced platelet aggregation 25% at a concentration of 50 nM.1 Doses of 10 mg/kg (oral) or 1 mg/kg (intraduodenal) have been shown to prevent rabbit carotid artery thrombosis.WARNING This product is not for human or veterinary use. | [Definition]
ChEBI: Benzoic acid, 3-[(e)-[(3ar,4s,5s,6ar)-4-[(1e,3r)-3-cyclohexyl-3-hydroxy-1-propen-1-yl]hexahydro-5-hydroxy-2(1h)-pentalenylidene]methyl]-, rel- is a monoterpenoid. | [References]
[1] MAURIN N. Influence on platelet activity and red cell fluidity of epoprostenol and two stable prostacyclin analogues in vitro.[J]. Arzneimittel-Forschung-Drug Research, 1986, 36 8: 1180-1183.
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