| Identification | Back Directory | [Name]
cinnamedrine | [CAS]
90-86-8 | [Synonyms]
cinnamedrine
N - CINNAMYL - L - EPHEDRINE
α-[1-[Methyl(3-phenyl-2-propenyl)amino]ethyl]benzenemethanol
Benzenemethanol, α-[1-[methyl(3-phenyl-2-propen-1-yl)amino]ethyl]- | [EINECS(EC#)]
202-021-2 | [Molecular Formula]
C19H23NO | [MDL Number]
MFCD00127843 | [MOL File]
90-86-8.mol | [Molecular Weight]
281.39 |
| Hazard Information | Back Directory | [Originator]
Midol Tab,Sterling Winthrop | [Manufacturing Process]
8.0 g of 1-phenyl-2-methylaminopropanol-1 are dissolved in 30 ml of warm
benzene and the solution is mixed with 5.0 g of cinnamylbromide. It isallowed to stand for 2 h at room temperature; the whole is then filtered with
suction to eliminate the phenylmethylaminopropanol hydrobromide formed
and the filtrate is shaken out with dilute hydrochloric acid, while adding such a
quantity of water that the thick oil drops which separate are dissolved. The
aqueous extract is filtered until it is clear, rendered alkaline by means of
ammonia, shaken with ether, the ether is distilled off, the residue is
recrystalized, so 1-phenyl-2-methyl-cinnamylaminopropanol-1 was obtained.
In practice it is usually used as hydrochloride. | [Therapeutic Function]
Smooth muscle relaxant |
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