| Identification | Back Directory | [Name]
BCP | [CAS]
901773-91-9 | [Synonyms]
3-Benzidino-6-(4-chlorophenyl)pyridazine
N4-(6-(4-Chlorophenyl)pyridazin-3-yl)-[1,1'-biphenyl]-4,4'-diamine
[1,1'-Biphenyl]-4,4'-diamine, N4-[6-(4-chlorophenyl)-3-pyridazinyl]- | [Molecular Formula]
C22H17ClN4 | [MDL Number]
MFCD11046030 | [MOL File]
901773-91-9.mol | [Molecular Weight]
372.85 |
| Chemical Properties | Back Directory | [Boiling point ]
626.0±55.0 °C(Predicted) | [density ]
1.300±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: >14mg/mL | [form ]
solid | [pka]
4.21±0.10(Predicted) | [color ]
light yellow | [InChI]
1S/C22H17ClN4/c23-18-7-1-17(2-8-18)21-13-14-22(27-26-21)25-20-11-5-16(6-12-20)15-3-9-19(24)10-4-15/h1-14H,24H2,(H,25,27) | [InChIKey]
ABGCSSPCKSVMHI-UHFFFAOYSA-N | [SMILES]
Nc1ccc(cc1)-c2ccc(Nc3ccc(nn3)-c4ccc(Cl)cc4)cc2 |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
22 | [RIDADR ]
UN 2811 6.1 / PGIII | [WGK Germany ]
3 | [Storage Class]
6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | [Hazard Classifications]
Acute Tox. 3 Oral |
| Hazard Information | Back Directory | [Biochem/physiol Actions]
3-Benzidino-6-(4-chlorophenyl)pyridazine is an inhibitor of delayed rectifier and transient outward potassium currents. The IC50 values for the blocking action of BCP on IKDR and IKA was calculated as 7.13 μM and 0.55 μM, respectively in acutely isolated rat hippocampal pyramidal neurons by using whole-cell patch-clamp technique. The parent compound, minaprine (Cat. No. M3157), has selective affinity for M1 muscarinic receptors and possesses memory-enhancing properties and also acts as an antidepressant. |
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