Identification | Back Directory | [Name]
tert-Butyl 3-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-4,5-dihydroisoxazole-3-carboxamido)butanoate | [CAS]
902146-11-6 | [Synonyms]
CBM 301940 tert-Butyl 3-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-4,5-dihydroisoxazole-3-carboxamido)butanoate | [Molecular Formula]
C15H20F6N2O5 | [MOL File]
902146-11-6.mol | [Molecular Weight]
422.32 |
Chemical Properties | Back Directory | [density ]
1.43±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
9.06±0.29(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Uses]
CBM-301940 (compound 5) is an orally active malonate CoA decarboxylase (MCD) inhibitor with IC50 value of 23 nM. CBM-301940 can be used in the study of cardiovascular diseases[1]. | [storage]
Store at -20°C | [References]
[1] Cheng JF, et al. Discovery of potent and orally available malonyl-CoA decarboxylase inhibitors as cardioprotective agents. J Med Chem. 2006 Jul 13;49(14):4055-8. doi: 10.1021/jm0605029. PMID: 16821767. DOI:10.1021/jm0605029 |
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Company Name: |
R&D Systems, Inc
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Tel: |
18003437475 18003437475 |
Website: |
www.rndsystems.com |
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