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902146-11-6

902146-11-6 Structure

902146-11-6 Structure
IdentificationBack Directory
[Name]

tert-Butyl 3-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-4,5-dihydroisoxazole-3-carboxamido)butanoate
[CAS]

902146-11-6
[Synonyms]

CBM 301940
tert-Butyl 3-(5-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-4,5-dihydroisoxazole-3-carboxamido)butanoate
[Molecular Formula]

C15H20F6N2O5
[MOL File]

902146-11-6.mol
[Molecular Weight]

422.32
Chemical PropertiesBack Directory
[density ]

1.43±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

9.06±0.29(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

CBM-301940 (compound 5) is an orally active malonate CoA decarboxylase (MCD) inhibitor with IC50 value of 23 nM. CBM-301940 can be used in the study of cardiovascular diseases[1].
[storage]

Store at -20°C
[References]

[1] Cheng JF, et al. Discovery of potent and orally available malonyl-CoA decarboxylase inhibitors as cardioprotective agents. J Med Chem. 2006 Jul 13;49(14):4055-8. doi: 10.1021/jm0605029. PMID: 16821767. DOI:10.1021/jm0605029
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