| Chemical Properties | Back Directory | [Boiling point ]
635.0±55.0 °C(Predicted) | [density ]
1.212±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
14.22±0.20(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Description]
MMV019313 is a highly specific inhibitor of the bifunctional Farnesyl/Geranylgeranyl Diphosphate Synthase (FPPS/GGPPS). | [Uses]
MMV019313 is a potent, non-bisphosphonate inhibitor of farnesyl/geranylgeranyl diphosphate synthase (FPPS/GGPPS) with an IC50 of 0.82 μM. MMV019313 has activity against P. falciparum (Parasite)[1]. | [References]
[1] Kabeche S, et al. Nonbisphosphonate inhibitors of Plasmodium falciparum FPPS/GGPPS. Bioorg Med Chem Lett. 2021 Jun 1;41:127978. DOI:10.1016/j.bmcl.2021.127978 |
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| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Website: |
www.chemicalbook.com/showsupplierproductslist927327/0_en.htm |
| Company Name: |
Biorbyt Ltd.
|
| Tel: |
+44 (0)1223 859 353 |
| Website: |
http://www.biorbyt.com |
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