| Identification | Back Directory | [Name]
EC 1.6.2.4 | [CAS]
9039-06-9 | [Synonyms]
EC 1.6.2.4
CYTOCHROME P450 REDUCTASE
napdh-cytochromep-450reductase
CYTOCHROME P450 REDUCTASE HUMAN
NADPH: FERRIHEMOPROTEIN OXIDOREDUCTASE
cytochrome P450 reductase from rabbit*liver induc
CYTOCHROME P450 REDUCTASE FROM RABBITLIV ER INDUCED
cytochrome p450 reductase from rabbit liver induced with phenobarbital
Cytochrome P450 Reductase from rabbit liver induced with phenobarbital buffered aqueous glycerol solution | [MDL Number]
MFCD01093329 |
| Hazard Information | Back Directory | [Uses]
Human cytochrome P450 reductase has been used in a study to assess the biocatalytic synthesis and structure elucidation of cyclized metabolites of the deacetylase inhibitor panobinostat (LBH589). Human cytochrome P450 reductase has also been used in a study to investigate the effects of coupled motions on electrons along the human microsomal P450 chains. | [General Description]
This human, recombinant protein is isolated from insect cells infected with a baculovirus containing the cDNA for human cytochrome P450 reductase. It is purified by affinity chromatography. | [Biochem/physiol Actions]
The enzyme catalyses electron transfer to cytochrome P450. This system plays a major role in detoxification of drugs and xenobiotics, activation of carcinogens, and metabolism of endogenous substrates such as steroids. |
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