| Identification | Back Directory | [Name]
ATN 161 TFA salt | [CAS]
904763-27-5 | [Synonyms]
ATN161 TFA salt
ATN-161 TFA salt
ATN 161 TFA salt
ATN-161 Trifluoroacetate
ATN-161 trifluoroacetate salt | [Molecular Formula]
C25H36F3N9O10S | [MOL File]
904763-27-5.mol | [Molecular Weight]
711.668 |
| Chemical Properties | Back Directory | [Melting point ]
>229°C (dec.) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
Water (Slightly, Heated, Sonicated) | [form ]
Solid | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
ATN 161 is an α5β1 integrin inhibitor that has advanced to phase II clinical trials to treat solid tumors. | [in vivo]
The preliminary experiments with α5β1-negative human colon cancer xenografts (HT29) show that treatment with ATN-161 significantly reduces tumor weight and vessel density[1]. Injection of ATN-161 after laser photocoagulation inhibits choroidal neovascularization (CNV) leakage and neovascularization to an extent similar to AF564[2]. | [storage]
Store at -20°C |
|
| Company Name: |
InvivoChem
|
| Telephone: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
| Company Name: |
Combio (Suzhou) Ltd.
|
| Telephone: |
17751201929; 17751201929 |
| Website: |
http://www.combiosz.com/ |
|