| Identification | Back Directory | [Name]
KGZHRAVDXGQUQM-WCQGTBRESA-N | [CAS]
907543-25-3 | [Synonyms]
AZD-5099
Abecarnil Impurity 4
KGZHRAVDXGQUQM-WCQGTBRESA-N | [Molecular Formula]
C21H27Cl2N5O6S | [MDL Number]
MFCD28902199 | [MOL File]
907543-25-3.mol | [Molecular Weight]
548.44 |
| Hazard Information | Back Directory | [Uses]
AZD5099, an antibacterial agent, is a potent and selective bacterial topoisomerase II inhibitor. AZD5099 potently inhibits the infections caused by Gram-positive and fastidious Gram-negative bacteria[1]. | [IC 50]
Topoisomerase II | [References]
[1] Gregory S Basarab, et al. Optimization of pyrrolamide topoisomerase II inhibitors toward identification of an antibacterial clinical candidate (AZD5099). J Med Chem. 2014 Jul 24;57(14):6060-82. DOI:10.1021/jm500462x |
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