| Identification | Back Directory | [Name]
ATRIOPEPTIN III (RAT) | [CAS]
90817-13-3 | [Synonyms]
atriopeptin24
ATRIOPEPTIN III
ANP (5-28), RAT
Rat atriopeptin-24
Rat atriopeptin III
ALPHA-ANF 5-28, RAT
Atriopeptin-24【rat】
ATRIOPEPTIN III (RAT)
SSCFGGRIDRIGAQSGLGCNSFR
ANF【Atriopeptin III rat】
Rat atriopeptin(103-126)
Atriopeptin III, ≥90% (HPLC)
Atrial natriuretic peptide-24 (rat)
ATRIOPEPTIN III (RAT, RABBIT, MOUSE)
ATRIAL NATRIURETIC PEPTIDE (5-28) RAT
Atrial Natriuretic Peptide Fragment 5-28
Atrial natriureticpeptide-24 (rat) (9CI)
Atrial natriuretic factor【Atriopeptin III rat】
SSCFGGRIDRIGAQSGLGCNSFRY (DISULFIDE BRIDGE: 3-19)
SER-SER-CYS-PHE-GLY-GLY-ARG-ILE-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR
H-SER-SER-CYS-PHE-GLY-GLY-ARG-ILE-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR-OH
SER-SER-CYS-PHE-GLY-GLY-ARG-ILE-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER(DISULFIDE BRIDGE:CYS3-CYS19)
H-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH, (Disulfide bond)
SER-SER-CYS-PHE-GLY-GLY-ARG-ILE-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR(DISULFIDE BRIDGE:CYS3-CYS19)
Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr (Disulfide bridge Cys7-Cys23)
H-SER-SER-CYS-PHE-GLY-GLY-ARG-ILE-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR-OH (DISULFIDE BRIDGE: 3-19)
L-Ser-L-Ser-L-Cys-L-Phe-Gly-Gly-L-Arg-L-Ile-L-Asp-L-Arg-L-Ile-Gly-L-Ala-L-Gln-L-Ser-Gly-L-Leu-Gly-L-Cys-L-Asn-L-Ser-L-Phe-L-Arg-L-Tyr-OH
Atriopeptin III (rat) H-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH (Disulfide bond)
L-Ser-L-Ser-L-Cys-L-Phe-Gly-Gly-L-Arg-L-Ile-L-Asp-L-Arg-L-Ile-Gly-L-Ala-L-Glu(NH2)-L-Ser-Gly-L-Leu-Gly-L-Cys-L-Asp(NH2)-L-Ser-L-Phe-L-Arg-L-Tyr-OH
SER-SER-CYS-PHE-GLY-GLY-ARG-ILE-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR: SSCFGGRIDRIGAQSGLGCNSFRYDISULFIDE BRIDGE CYS7-CYS23
L-Ser-L-Ser-L-Cys(1)-L-Phe-Gly-Gly-L-Arg-L-Ile-L-Asp-L-Arg-L-Ile-Gly-L-Ala-L-Glu(NH2)-L-Ser-Gly-L-Leu-Gly-L-Cys(1)-L-Asp(NH2)-L-Ser-L-Phe-L-Arg-L-Tyr-OH | [Molecular Formula]
C107H165N35O34S2 | [MDL Number]
MFCD00076237 | [MOL File]
90817-13-3.mol | [Molecular Weight]
2549.8 |
| Chemical Properties | Back Directory | [density ]
1.54 | [storage temp. ]
-15°C | [Sequence]
Ser-Ser-Cys-Phe-Gly-Gly-Arg-Ile-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr (Disulfide bridge:Cys3-Cys19) |
| Hazard Information | Back Directory | [Uses]
Atriopeptin III (ANP 127-150) (rat), a 24-amino acid atrial peptide, is a potent vasodilator and natriuretic/diuretic agent. Atriopeptin III (rat) improves renal functions and decreases blood pressure in a ureter-obstructed rat kidney model. Atriopeptin III (rat) can be used for research of chronic renal failure[1]. | [References]
[1] Olsen UB, et al. Atriopeptin III improves renal functions in a ureter-obstructed rat kidney model. Eur J Pharmacol. 1986 Mar 18;122(2):191-6. DOI:10.1016/0014-2999(86)90102-0
[2] Cole BR, et al. Atriopeptin III. A potent natriuretic, diuretic, and hypotensive agent in rats with chronic renal failure. J Clin Invest. 1985 Dec;76(6):2413-5. DOI:10.1172/JCI112254 |
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