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90954-53-3

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90954-53-3 Structure

90954-53-3 Structure
IdentificationBack Directory
[Name]

ALA-CYS-ASP-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2
[CAS]

90954-53-3
[Synonyms]

CGRPI
CGRP (HUMAN)
CGRP-I, HUMAN
CGRP-1, HUMAN
a-CGRP (huMan)
α-CGRP (huMan)
ALPHA-CGRP (HUMAN)
α-CGRP (huMan) CGRP-I (huMan)
M.W. 3789.36 C163H267N51O49S2
CGRP-I (HUMAN) TRIFLUOROACETATE SALT
CALCITONIN GENE RELATED PEPTIDE HUMAN
Human calcitonin gene-related peptide 1
ALPHA-CGRP (HUMAN) TRIFLUOROACETATE SALT
CALCITONIN GENE-RELATED PEPTIDE-I, HUMAN
ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF-NH2
α-CGRP (mouse, rat) trifluoroacetate salt
α-Calcitonin gene-related peptide (human)
ALPHA-CALCITONIN GENE RELATED PEPTIDE, HUMAN
Calcitonin gene related peptide human, ≥95% (HPLC)
α-CGRP (human)|Calcitonin Gene Related Peptide II, human
ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF-NH2 (DISULFIDE BRIDGE: 2-7)
CalcitoninGeneRelatedPeptidehuMan,CalcitoninGeneRelatedPeptidehuMa
ALPHA-CALCITONIN GENE-RELATED PEPTIDE (HUMAN) TRIFLUOROACETATE SALT
Calcitonin Gene-Related Peptide-I, Human - CAS 90954-53-3 - Calbiochem
ALA-CYS-ASP-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2
Ala-Cys-Asn-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Met-Val-Lys-Ser-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2
H-ALA-CYS-ASP-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2
VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2: VTHRLAGLLSRSGGVVKNNFVPTNVGSKAF-NH2
ALA-CYS-ASP-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2 USP/EP/BP
ALA-CYS-ASP-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2(CYS&CYS BRIDGE)
H-ALA-CYS-ASP-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2 (DISULFIDE BRIDGE: 2-7)
ALA-CYS-ASN-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-MET-VAL-LYS-SER-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2(DISULFIDE BRIDGE CYS2-CYS7)
Ala-Cys-Asp-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2 (Disulfide bridge Cys2-Cys7)
Alpha-CGRP (human) trifluoroacetate salt H-Ala-Cys-Asp-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2 trifluoroacetate salt (Disulfide bond)
[Molecular Formula]

C163H267N51O49S2
[MDL Number]

MFCD00285485
[Molecular Weight]

3789.31
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[solubility ]

5% acetic acid: 1mg/mL
[form ]

powder
[color ]

White to off-white
[Water Solubility ]

Soluble in water or 1% acetic acid at 1mg/ml.
[Sequence]

Ala-Cys-Asp-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2 (Disulfide bridge:Cys2-Cys7)
[InChIKey]

DNKYDHSONDSTNJ-XJVRLEFXSA-N
Safety DataBack Directory
[WGK Germany ]

3
[Storage Class]

11 - Combustible Solids
Hazard InformationBack Directory
[Uses]

Calcitonin Gene Related Peptide is used as a potent, long-lasting vasodilator, activation of CGRP receptors on pancreatic β-cells increases plasma levels of pancreatic enzymes.
[Biochem/physiol Actions]

Potent, long-lasting vasodilator; activation of CGRP receptors on pancreatic β-cells increases plasma levels of pancreatic enzymes.
[in vivo]

α-CGRP(human) (Intravenous infusion; 0.03 nmol/kg/min; 60 min) can cause significant hypotension and tachycardia accompanied by falls in renal and mesenteric flows, but an increase in hindquarters flow, and a transient renal, sustained hindquarters vasodilatation and a mesenteric vasoconstriction in conscious rats[2].

[storage]

Desiccate at -20°C
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