| Identification | Back Directory | [Name]
thonzylamine | [CAS]
91-85-0 | [Synonyms]
NCI-C-60708
Brn 0284655
Neohetramine
thonzylamine
Einecs 202-103-8
63-56-9 (Mono-hydrochloride)
2-piriMidina
2-((2-(Dimethylamino)ethyl)(p-methoxybenzyl)amino)pyrimidine
N-[2-(Dimethylamino)ethyl]-N-(4-methoxybenzyl)pyrimidin-2-amine
N,N-Dimethyl-N'-(p-methoxybenzyl)-N'-(2-pyrimidyl)ethylenediamine
Ethylenediamine, N-(p-methoxybenzyl)-N',N'-dimethyl-N-2-pyrimidinyl-
N,N-Dimethyl-N'-(4-methoxybenzyl)-N'-(2-pyrimidinyl)-1,2-ethanediamine
N1-(4-Methoxybenzyl)-N2,N2-dimethyl-N1-(pyrimidin-2-yl)ethane-1,2-diamine
N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-pyrimidin-2-ylethane-1,2-diamine
N-[(4-Methoxyphenyl)methyl]-N',N'-dimethyl-N-(2-pyrimidinyl)-1,2-ethanediamine
1,2-Ethanediamine, N-((4-methoxyphenyl)methyl)-N',N'-dimethyl-N-2-pyrimidinyl- | [EINECS(EC#)]
202-103-8 | [Molecular Formula]
C16H22N4O | [MDL Number]
MFCD00865672 | [MOL File]
91-85-0.mol | [Molecular Weight]
286.38 |
| Chemical Properties | Back Directory | [Boiling point ]
428.74°C (rough estimate) | [density ]
1.0426 (rough estimate) | [refractive index ]
1.5850 (estimate) | [storage temp. ]
Hygroscopic, Refrigerator, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Oil | [pka]
pKa 2.17 (Uncertain);8.96 (Uncertain) | [color ]
Light Brown to Brown | [Water Solubility ]
5.441g/L(37.5 ºC) | [Stability:]
Hygroscopic | [CAS DataBase Reference]
91-85-0 | [EPA Substance Registry System]
Thonzylamine (91-85-0) |
| Hazard Information | Back Directory | [General Description]
An oily liquid. Used (in the form of the hydrochloride) as an antihistaminic. | [Reactivity Profile]
thonzylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides. | [Health Hazard]
ACUTE/CHRONIC HAZARDS: Toxic. Hazardous decomposition products. | [Uses]
Thonzylamine is a selective H1-histamine receptor anatagonists. Tropine esterase inhibitor. | [Definition]
ChEBI: N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-(2-pyrimidinyl)ethane-1,2-diamine is a member of methoxybenzenes. | [Synthesis]
Thonzylamine is synthesized by treating
the sodium salt of 2-(4-methoxybenzyl)aminopyrimidine
with N,N-dimethyl-2-chloroethylamine
. | [storage]
Store at -20°C |
|
| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
|