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910297-51-7

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910297-51-7 Structure

910297-51-7 Structure
IdentificationBack Directory
[Name]

N-Deshydroxyethyl Dasatinib
[CAS]

910297-51-7
[Synonyms]

Dasatinib Impurity A
Dasatinib metabolite M4
N-Deshydroxyethyl Dasatinib
N-(2-Chloro-6-methylphenyl)-2-[[2-methyl-6-(1-piperazinyl)-4-pyrimidinyl]amino]-5-thiazolecarboxamide
[Molecular Formula]

C20H22ClN7OS
[MDL Number]

MFCD18252607
[MOL File]

910297-51-7.mol
[Molecular Weight]

443.95
Chemical PropertiesBack Directory
[Appearance]

White Solid
[Melting point ]

>300°C
[density ]

1.403±0.06 g/cm3(Predicted)
[storage temp. ]

Refrigerator
[solubility ]

DMSO (Slightly), Methanol (Slightly, Heated)
[form ]

Solid
[pka]

10.94±0.70(Predicted)
[color ]

White to Off-White
[CAS DataBase Reference]

910297-51-7
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Uses]

A metabolite of Dasatinib. Used in the treatment of cancers and immune diseases
[in vivo]

1.19Pharmacokinetic Parameters of N-Deshydroxyethyl Dasatinib in Wistar Rats[2].
AnalyteCmax (ng/mL)AUC0-t (h*ng/mL)AUC0-inf (h*ng/mL)Tmax (h)T1/2 (h)Kel (h-1)
N-Deshydroxyethyl Dasatinib2.058.723.92.010.2930.072
Spectrum DetailBack Directory
[Spectrum Detail]

N-Deshydroxyethyl Dasatinib(910297-51-7)1HNMR
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