| Identification | Back Directory | [Name]
Benzamide, 2-chloro-N-[4-[6-[(cyclopropylcarbonyl)amino]-1H-benzimidazol-2-yl]phenyl]- | [CAS]
911211-69-3 | [Synonyms]
Benzamide, 2-chloro-N-[4-[6-[(cyclopropylcarbonyl)amino]-1H-benzimidazol-2-yl]phenyl]- | [Molecular Formula]
C24H19ClN4O2 | [MOL File]
911211-69-3.mol | [Molecular Weight]
430.89 |
| Hazard Information | Back Directory | [Uses]
NR2E3 agonist 1 (Compound 11a) is a small molecule agonist of the photoreceptor-specific nuclear receptor (NR2E3) with an EC50 value of less than 200 nM. NR2E3 agonist 1 can be used in retinitis pigmentosa research[1]. | [References]
[1] Wolkenberg SE, et al. Identification of potent agonists of photoreceptor-specific nuclear receptor (NR2E3) and preparation of a radioligand. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5001-4. DOI:10.1016/j.bmcl.2006.07.056 |
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