| Identification | Back Directory | [Name]
Methyl-piperidino-pyrazole hydrate | [CAS]
911295-24-4 | [Synonyms]
MPP dihydrochloride hydrate
Methyl-piperidino-pyrazole hydrate
1,3-Bis(4-hydroxyphenyl)-4-methyl-5-[4-(2-piperidinylethoxy)phenol]-1H-pyrazole dihydrochloride hydrate | [Molecular Formula]
C29H32ClN3O3 | [MDL Number]
MFCD06411603 | [MOL File]
911295-24-4.mol | [Molecular Weight]
506.04 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: soluble ≥20mg/mL | [form ]
white powder | [color ]
White to off-white | [InChIKey]
FWDNPWVVRVSJQH-UHFFFAOYSA-N | [SMILES]
Cl.Cl.Cc1c(nn(-c2ccc(O)cc2)c1-c3ccc(OCCN4CCCCC4)cc3)-c5ccc(O)cc5 |
| Hazard Information | Back Directory | [Uses]
MPP dihydrochloride hydrate has been used as an estrogen receptor α antagonist:
- in human breast cancer MCF-7 cells
- to pre-treat endometrial ex vivo organ cultures (EVOCs)
- to treat pituitary glands to monitor luteinizing hormone secretion
| [Uses]
MPP Dihydrochloride is a pharmacological estrogen receptor antagonist. It cannot block EE2 induced luciferase activity with any isoform of zebrafish estrogen receptor. | [General Description]
Methyl-piperidino-pyrazole hydrate (MPP) is prepared from a methyl-pyrazole-triol (MPT), a pyrazole triol. | [Biochem/physiol Actions]
MPP dihydrochloride is a specific estrogen receptor α antagonist. | [storage]
+4°C (desiccate) |
|
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Bide Pharmatech Ltd.
|
| Telephone: |
400-1647117 13681763483 |
| Website: |
https://www.bidepharm.com/ |
|